Freeze-drying txheej txheem yog cov txheej txheem ua kom kub thiab huab hwm coj mus hloov, koom nrog tub yees, nqus tsev, khoom siv hluav taws xob, tshuaj lom neeg, tshuaj cryogenic thiab lwm yam kev qhuab qhia, nrog cov txheej txheem cov ntsiab lus siab thiab cov txheej txheem khov-ziab kom qhuav.Hauv cov tshuaj suav, tshuaj noj thiab lwm yam lag luam, lub tshuab nqus tsev khov yog ib qho khoom siv nrov tshaj plaws.
Cov txheej txheem ua haujlwm, lub tshuab nqus tsev ua lub tshuab nqus dej khov yog lub thawv tshiab, uas ua ke nrog lub tshuab ua kom lub tub yees, lub tshuab nqus tsev, lub tshuab ua kom sov cov roj cua kub thiab cov txheej txheem noo noo tshem tawm. Nws tuaj yeem ua qhov siv ntawm qhov chaw hauv lub thawv los khaws cov khoom siv kom zoo rau qhov ziab kom qhuav kom qhuav.Thaum tam sim no, lub tshuab nqus tsev khov yog qhov tsim nyog rau kev ziab ntawm cov ntaub ntawv raw, Suav tshuaj, tshuaj intermediates, zaub mov thiab lwm yam ntaub ntawv.
Prefreezing tus nqi ntawm cov ntaub ntawv
Nws to taub tias qhov khoom ua ntej txias yog qhov ua ntej thaum cov lyophilizer ua haujlwm.Qhov ua ntej khov yuav muab faib ua khov khov thiab qeeb khov. Qhov luaj li cas ntawm cov qauv siv lead ua thaum khov khov cuam tshuam tag nrho cov ziab thiab qhov xaus ntawm qhov khoom tawg tom qab ziab.
Tshwj xeeb, kev ua kom khov sai thiab qeeb txheej txheem khov muaj cov sib txawv li no: cov dej khov sai tsim cov dej khov ua kom me me, khov khov ua rau cov dej khov khov loj dua. Lub sijhawm khov khov ua rau qhov qis qis sublimation tus nqi thiab qhov xav tau ceev nrawm dua.Lub khov ua kom tau qhov sib nrawm nrawm thiab qhov ntsuas tus lej qeeb.
Raws li, qhov kev lag luam taw qhia tawm, qhov ceev nrawm uas yuav tsum tau ua yuav tsum tuav raws cov khoom siv yog.
Siab hauv chav ziab
Kev lag luam hais tias tus nqi ntawm lub siab nyob rau hauv chav tsev ziab ncaj qha cuam tshuam rau tus nqi ntawm tshav kub thiab huab hwm coj hloov (dej tso pa tawm) .Qhov hais txog qhov hloov huab hwm coj, qis dua yog qhov zoo dua, thaum lub siab hloov siab dua zoo dua rau kev hloov tshav kub.
Txij li huab hwm coj hloov mus rau feem ntau yog txiav txim siab los ntawm qhov kub thiab siab ntawm sublimation interface thiab saum npoo ntawm cov txheej qhuav, muaj feem ntau ob txoj haujlwm los txhim kho tus nqi dej vauv khiav tawm hauv txheej txheej qhuav: nce qhov kub ntawm sublimation interface thiab nce lub siab ntawm dej vapor ntawm qhov interface.Los kom ua kom lub tshuab nqus tsev ntawm lub tshuab ziab khaub ncaws, txo cov vapor siab rau ntawm txheej txheej kom qhuav.
Daim ntawv ntawm cov khoom siv
Nws tau tshaj tawm tias nyob rau hauv cov txheej txheem khov-khov, txheej txheem khov-khov yog feem ntau muab faib ua cov khoom ua kua thiab ua kua.Qhov ntau qhov nruab nrab ntawm cov khib nyiab thiab cov dej ntws sib xyaw ua ke cuam tshuam rau lub sijhawm txias ntawm cov ntaub ntawv.
Ntub dej reloading muaj peev xwm
Nws paub tias thaum cov khoom khov-qhuav, muaj qhov sib piv ntawm cov cheeb tsam hauv cheeb tsam rau cov khoom tuab tom qab muab tso rau hauv lub thawv.Hauv cov khoom kom qhuav, lub ntim rov qab ntub dej ntawm lub ziab kom qhuav ntawm ib cheeb tsam yog qhov tseem ceeb yam uas txiav txim siab lub sij hawm ziab.
Feem ntau, cov thinner cov tuab ntawm cov khoom, lub nrawm dua kub thiab huab hwm coj hloov, thiab lub sijhawm luv dua lub sijhawm ziab.Yuav li cas, yog tias cov khoom nyias, yuav muaj tsawg dua cov ntaub ntawv qhuav rau ib pob rau ib qho chaw khov-ziab, uas yuav tsis zoo ua kom muaj txiaj ntsig rau cov khoom tso tawm rau ib cheeb tsam khov-ziab hauv ib cheeb tsam thiab ib lub sijhawm.Yog li ntawd yuav tsum tau nqa ntawm kev xav dav raws li cov khoom siv.