Lub tshuab nqus tsev lub tshuab nqus tsev yog tsim rau ziab cov khoom siv qib siab, cov khoom siv hauv Suav teb, biology, zaub qus, zaub dehydrated, zaub mov, txiv hmab txiv ntoo, tshuaj, tshuaj intermediates thiab lwm yam ntaub ntawv.
Cia kuv qhia txoj hauv kev ua haujlwm ntawm lub tshuab nqus tsev vacuum freeze dryer:
Tom qab pib lub tshuab, muab cov khoom tso rau hauv lub thawv khoom kom khov. Thaum lub sijhawm khov ntawm cov khoom siv, ntawm ib sab, lub tshuab nqus tsev vacuumizes tshem tawm ib feem ntawm cov dej; ntawm qhov tod tes, thaum cov khoom yog khov, cov dej uas muaj nyob rau hauv ib co molecules yog tawm mus rau lub nto ntawm cov khoom yog khov.
Tom qab ua tau raws li qhov yuav tsum tau ua kom khov, lub tshuab cua sov ua kom sov thiab ziab cov khoom, thiab cov dej uas muaj nyob hauv cov khoom raug coj mus rau qhov khov thiab khaws lub thawv los ntawm lub tshuab nqus tsev kom khov, thiaj li ua tau raws li qhov xav tau kom khov thiab ziab ntawm cov khoom.
Freeze-drying yog hais txog cov txheej txheem ntawm kev tshem tawm cov dej noo lossis lwm cov kuab tshuaj los ntawm cov khoom siv roj ntsha khov los ntawm sublimation. Sublimation yog hais txog cov txheej txheem uas cov kuab tshuaj, xws li dej, zoo li cov dej khov qhuav, hloov ncaj qha los ntawm cov khoom hauv lub xeev mus rau lub xeev gaseous yam tsis mus dhau lub xeev cov kua.
Cov khoom tau los ntawm khov-drying yog hu ua lyophilisate, thiab cov txheej txheem hu ua freeze-drying. Kev ziab ib txwm tuaj yeem ua rau cov khoom ua kom qis, ua kom puas hlwb.
Cov qauv ntawm cov qauv tsis raug puas tsuaj thaum lub sij hawm khov-qhuav vim tias cov khoom siv tau txais kev txhawb nqa los ntawm cov dej khov hauv lawv qhov chaw. Raws li cov dej khov sublimates, nws tawm qhov pores hauv cov khoom seem qhuav.
Qhov no khaws cia qhov kev ncaj ncees ntawm cov khoom siv roj ntsha thiab cov qauv tshuaj thiab nws cov haujlwm. Hauv chav kuaj, lyophilization muaj ntau yam kev siv, thiab nws yog qhov tseem ceeb hauv ntau daim ntawv thov biochemical thiab tshuaj.
Nws yog siv los khaws cov khoom siv roj ntsha mus sij hawm ntev, xws li kab lis kev cai microbial, enzymes, ntshav, thiab tshuaj, uas khaws lawv cov khoom siv roj ntsha thiab cov qauv ntxiv rau kev khaws cia ntev. Txog rau qhov kawg no, lyophilization yog siv los npaj cov ntaub so ntswg rau kev tshawb fawb xws li electron microscopy kev tshawb fawb.
Kev ziab kom qhuav kuj tseem siv rau hauv kev tshuaj ntsuam tshuaj kom tau txais cov qauv hauv lub xeev qhuav, los yog ua kom pom tseeb cov qauv kom muaj kev ntsuam xyuas rhiab heev. Freeze-drying stabilizes qhov muaj pes tsawg leeg ntawm cov qauv yam tsis hloov cov tshuaj muaj pes tsawg leeg, ua rau nws yog ib qho zoo tagnrho analytical pab.